In a large skillet, brown the ground beef over medium-high heat until no longer pink, breaking it up as it cooks.
Add the tomato sauce, ketchup, onion, garlic, chili, and mustard powders. Bring to a boil. Reduce heat and let simmer for 10 minutes.
Put a large oven proof skillet in the oven and preheat the oven to 350 degrees. When the oven has preheated, remove the skillet, and fill with the tortilla chips. Pour the sauce over the chips, the beans over the sauce, then sprinkle the cheeses evenly over the top. Bake for 8-10 minutes or until the cheese melts.
Top with the salsa and jalapeño slices. Serve immediately.