Gluten-Free Queso Mac and Cheese on a gray plate with a casserole dish on the side on a wooden table

Easy Baked Gluten-Free Queso Mac & Cheese

Creamy Velveeta cheese, zesty tomatoes and chilies, tender gluten-free noodles, and crispy gluten-free breadcrumbs come together beautifully and simply in this Easy Baked Gluten-Free Queso Mac & Cheese recipe. You’re going to love the homestyle comfort food element of this one! AND this recipe is perfect for Cinco de Mayo because of its Mexican influence (tomatoes and chilies with Mexican blend cheese). 

This dish is a pour and bake type of meal – place the block of cheese in the center of the baking dish (yes, the whole block, not sliced!), pour the uncooked macaroni in, pour the tomatoes and chilies in (I used Hatch tomatoes and green chilies), sprinkle the cheese, pour the cream … put it in the oven and then finish it up with a topping of breadcrumbs.

The result is a melt-in-your-mouth, warm-your-soul, soothe-your-cravings, extraordinarily comforting dish that you’ll want to share with others.

Check out more gluten-free pasta recipes.

Gluten-Free Queso Mac and Cheese in a white casserole with a spoon holding a scoop of the macaroni and cheese

5 from 4 votes
Gluten-Free Queso Mac and Cheese on a gray plate with a casserole dish on the side on a wooden table
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Easy Baked Gluten-Free Queso Mac & Cheese Recipe

Prep Time10 mins
Cook Time50 mins
Total Time1 hr
Course: Main Course, Side Dish
Cuisine: American, Mexican
Servings: 6 servings
Calories: 1002kcal
Author: Gluten Free & More


  • Gluten-free nonstick cooking spray
  • 1 (16-ounce) block Velveeta cheese
  • 12 ounces gluten-free elbow macaroni
  • 1 (10-ounce) can Hatch Diced Tomatoes & Green Chilies, undrained
  • 4 cups shredded Mexican blend cheese
  • 4 cups cream or half-and-half
  • 2 teaspoons kosher or fine sea salt
  • 3 tablespoons unsalted butter
  • cups gluten-free panko breadcrumbs


  • Preheat oven to 350 degrees. Spray a 9 by 12-inch baking dish with cooking spray.
  • Place the block of Velveeta cheese in the middle of the baking dish. Add the macaroni around the cheese. Distribute the can of tomatoes and chilies over the top. Sprinkle with the Mexican blend cheese, pour the cream all over, sprinkle with salt and bake 25 minutes.
  • Melt the butter in a large skillet over medium heat. Add the breadcrumbs and cook, stirring occasionally, until golden brown.
  • Stir the macaroni mixture in the baking dish and continue to bake for another 20 minutes. Sprinkle the toasted breadcrumbs over the mixture and bake for another 5 minutes.


Nutrition Facts
Easy Baked Gluten-Free Queso Mac & Cheese Recipe
Amount Per Serving
Calories 1002 Calories from Fat 468
% Daily Value*
Fat 52g80%
Saturated Fat 30g150%
Trans Fat 1g
Cholesterol 166mg55%
Sodium 2816mg117%
Potassium 631mg18%
Carbohydrates 92g31%
Fiber 3g12%
Sugar 8g9%
Protein 45g90%
Vitamin A 1981IU40%
Vitamin C 6mg7%
Calcium 1476mg148%
Iron 1mg6%
* Percent Daily Values are based on a 2000 calorie diet.
Disclaimer: All nutrition facts on Gluten Free & More are meant only as a guide and may differ depending on product brands used or ingredient substitutions. Some errors may occur, so you are encouraged to confirm the recipe’s ingredient and nutrition suitability for your own diet.
Have you tried this recipe? Give it a star rating and let us know your thoughts in the Ratings & Reviews section below.
Tags: Breadcrumbs Cheese Chili Peppers Cinco de Mayo Comfort Food Hatch Chile Macaroni and Cheese Pasta Tomatoes
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